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Total number of cases passes 106 million

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  • The coronavirus outbreak started in Wuhan, China, in December 2019.
  • Known as SARS-CoV-2, the virus has resulted in additional than 106 million infections and greater than 2.3 million deaths.
  • SARS-CoV-2 an infection causes a respiratory sickness known as COVID-19.
  • COVID-19 has now been reported on each continent.
  • Keep updated with the newest analysis and details about COVID-19 here.
  • For vaccine info, go to our live vaccine updates article.

02/08/2021 09:05 GMT — South Africa halts AstraZeneca vaccine rollout

Officials in South Africa have paused the rollout of the AstraZeneca vaccine to healthcare employees. The transfer comes following the outcomes of a small trial, which point out that the vaccine just isn’t efficient in stopping mild-to-moderate sickness brought on by the variant that’s now dominant within the nation.

Find extra on this story in our live vaccine updates article.

02/08/2021 09:01 GMT — China report no new cases of COVID-19

Yesterday, for the primary time since December 16, 2020, Chinese officers reported no new domestically transmitted cases of COVID-19 on the mainland. On February 7, there have been 14 cases, all of which had been imported from abroad. Half of these occurred in Shanghai and the remainder in Guangdong province.

Read extra here.

02/05/2021 14:46 GMT — Tackling COVID-19 vaccine hesitancy amongst Black Americans

Read the complete MNT function here.

02/05/2021 09:03 GMT — Johnson & Johnson push for emergency use authorization 

Preliminary outcomes from scientific trials present that Johnson & Johnson’s single-dose vaccine candidate is secure and efficient. On Thursday, they urged the Food and Drug Administration (FDA) to contemplate emergency use authorization. The FDA have asked their impartial consultants to debate the small print on February 26.

Find extra in our live vaccine updates article.

02/05/2021 08:55 GMT — Some COVID-19 sufferers have a better danger of bleeding

Excessive blood clotting is a acknowledged function of extreme COVID-19. However, a brand new examine means that some hospitalized sufferers might also be weak to bleeding, which is related to an elevated danger of loss of life. The analysis seems within the journal Scientific Reports.

Read MNT’s protection of the examine here

02/04/2021 09:10 GMT — SARS-CoV-2 can affect metabolism by infecting pancreas cells

A brand new examine, which seems in Nature Metabolism, settles a long-standing debate. Using a multipronged method, the researchers show that SARS-CoV-2 can infect beta-cells, that are the pancreatic cells that produce insulin. They additionally confirmed that this an infection can disrupt beta-cell operate.

Although scientists initially thought of COVID-19 a illness of the lungs, they’ve proven that it impacts a spread of organs, together with the brain and heart.

There can be proof that COVID-19 impacts glucose metabolism. For occasion, a meta-analysis confirmed that extreme COVID-19 was related to elevated blood glucose. 

The authors conclude, “Our data identify the human pancreas as a target of SARS-CoV-2 infection and suggest that beta-cell infection could contribute to the metabolic dysregulation observed in patients with COVID-19.”

Read the complete paper here.

02/04/2021 09:05 GMT — Oxford-AstraZeneca engaged on vaccine to deal with SARS-CoV-2 variants

There is rising evidence that present vaccines are effective in opposition to SARS-CoV-2 variants. However, Oxford-AstraZeneca are engaged on a vaccine designed particularly to guard in opposition to these rising variants. They hope to have the altered vaccine prepared by fall 2021. 

Find extra in our live vaccines update article.

02/03/2021 09:09 GMT — COVID-19: Why are Asian and Black sufferers at larger danger?

A current study concludes that, even after accounting for different recognized danger components, resembling diabetes and hypertension, Black and Asian sufferers hospitalized with COVID-19 had been extra prone to want mechanical air flow and extra prone to die than white sufferers.

“As the impact of COVID-19 continues to be seen within our community, the importance of responding to the ethnic disparities unmasked during the COVID-19 pandemic is crucial to prevent entrenching and inflicting them on future generations,” explains Dr. Yize Wan, one of the examine authors.

Read MNT’s full protection of the examine here.

02/03/2021 09:04 GMT — Oxford-AstraZeneca shot 76% efficient for 3 months after single dose

Following a single dose, the Oxford-AstraZeneca vaccine is 76% efficient at stopping symptomatic an infection with SARS-CoV-2 for 3 months, in line with a brand new examine. The outcomes assist the United Kingdom’s method of leaving a 12-week hole between photographs. 

Read extra in our live vaccine updates article.

02/02/2021 15:32 GMT — The B.1.1.7 coronavirus picks up ‘worrying’ mutations within the UK

A report by Public Health England (PHE) describes 11 cases of a further mutation within the B.1.1.7 SARS-CoV-2 variant. The explicit mutation, known as E484Ok, can be present within the variants first recognized in Brazil and South Africa. 

Scientists first recognized the B.1.1.7 variant within the United Kingdom final 12 months. Some individuals check with it because the “U.K. variant.” Modeling information point out that this variant is extra prone to go from person to person. 

Additional variants that researchers recognized in South Africa and Brazil carry some of the identical mutations as B.1.1.7. What has set them aside till now’s the addition of the E484Ok mutation within the spike protein. It seems to make vaccines and monoclonal antibodies much less efficient at preventing off the virus. 

Prof. Jonathan Stoye, a bunch chief on the Francis Crick Institute in London, U.Ok. — whose laboratory research virus-host interactions — offered comments on the report by PHE: 

“The E484K mutation [has] now been identified in a small fraction of viruses carrying sequence differences defining the U.K. variant,” he says. “This suggests that the U.K. variant is now independently acquiring the E484K change.”

“From a virological standpoint, appearance of new variants by mutation during replication cannot be considered surprising. Whether this change will provide significant growth advantages for the novel virus causing it to predominate remains to be seen,” Prof. Stoye continues. “This report would seem to suggest that under conditions of very high levels of virus replication even the most stringent of border controls, although they may delay spread, are unlikely to prevent the appearance of new variants.” 

“This updated PHE report on the U.K. B.1.1.7 [variant] mentions the acquisition of the E484K mutation — which is a worrying development, though not entirely unexpected,” provides Dr. Julian Tang, a scientific virologist from the University of Leicester within the U.Ok. 

“This is another reason to follow the COVID-19 restrictions/infection control measures more strictly — otherwise not only can the virus continue to spread, it can also evolve,” he provides.

Read extra concerning the B.1.1.7 variant here.

02/02/2021 09:37 GMT — New masks guidelines within the US

Today, new masks guidelines come into impact within the United States. People should put on a face masks when they’re on trains, airplanes, buses, taxis, ferries, and ride-share automobiles. People should additionally put on them in stations, ports, airports, and different transport hubs.

The Centers for Disease Control and Prevention (CDC) define the foundations here. In a Federal Register Notice, the CDC clarify:

“This Order must be followed by all passengers on public conveyances […] traveling into, within, or out of the United States, as well as conveyance operators (e.g., crew, drivers, conductors, and other workers involved in the operation of conveyances) and operators of transportation hubs […] or any other area that provides transportation in the United States.”

Read extra from the CDC here.

02/02/2021 09:09 GMT — US officers won’t make immigration arrests at vaccination facilities

According to a statement, the Department of Homeland Security (DHS) think about vaccination websites “sensitive locations.” As such, the DHS won’t make routine immigration enforcement arrests at these facilities. They encourage everybody “regardless of immigration status” to obtain the vaccine when they’re eligible.

Find extra on this story in our live vaccine updates article.

02/01/2021 09:16 GMT — Johnson & Johnson vaccine candidate 66% efficient

According to an interim evaluation, which included information from 43,783 individuals, the Johnson & Johnson single-shot vaccine is 66% efficient in stopping average or extreme COVID-19 from 28 days after vaccination. Overall, the experimental vaccine was 85% efficient in stopping extreme illness. Importantly, nobody who obtained the vaccine candidate wanted hospital therapy or died.

Find extra on the the Johnson & Johnson vaccine here.

02/01/2021 09:10 GMT — WHO staff visits Wuhan moist markets

Yesterday, a number of consultants from the World Health Organization (WHO) visited the moist market in Wuhan, China, that’s linked to some of the earliest cases of COVID-19. They hope that this go to may present clues as to how the virus unfold so extensively.

Earlier of their journey, the consultants visited a museum devoted to the early days of COVID-19, in addition to two hospitals within the area and the Baishazhou market, one of the biggest moist markets in Wuhan.

Understanding the advanced genesis of SARS-CoV-2 is prone to be an extended mission, however the consultants hope that visits resembling these may illuminate additional avenues of investigation. 

As one of the staff, zoologist Dr. Peter Daszak, explains, the go to is “critical for our joint teams to understand the epidemiology of COVID-19 as it started to spread at the end of 2019.”

Read extra here.

01/29/2021 14:46 GMT — Addressing COVID-19 vaccine myths

Read the complete function here.

01/29/2021 09:09 GMT — Novavax vaccine reveals 89.3% efficacy

Novavax have introduced that, in line with an interim evaluation of Phase 3 scientific trials, their vaccine candidate demonstrates 89.3% efficacy. The evaluation included 62 cases of COVID-19, 56 of which occurred in the placebo group, and six within the vaccine group.

Find extra on this story in our stay vaccine updates article.

01/29/2021 09:00 GMT — South Africa variant detected within the US

Yesterday, the SARS-CoV-2 variant first recognized in South Africa was detected in two South Carolina residents. This is the primary time it has been detected within the United Sates. The two residents weren’t related and neither had just lately traveled.

According to Dr. Krutika Kuppalli, an infectious illnesses knowledgeable on the Medical University of South Carolina, in Charleston, that is significantly regarding as a result of it signifies that the variant is “probably more widespread.”

Read extra here.

01/28/2021 10:02 GMT — AAVCOVID vaccine candidate receives monetary enhance

The AAVCOVID Vaccine Program has produced a gene-based vaccine that’s storable at room temperature and seems to be efficient after one dose. A current inflow of as much as $2.1 million from the Bill & Melinda Gates Foundation will assist the corporate transfer the vaccine into part 1 scientific trials.

Find extra on this story in our stay vaccine updates article.

01/28/2021 09:13 GMT — Some states ease restrictions

In response to decreased an infection charges and hospitalization, some states are starting to ease restrictions. For occasion, in Michigan, eating places are open to indoor eating for the primary time in 10 weeks. However a 10 p.m. curfew is in place, and their capability is proscribed.

Gretchen Whitmer, Michigan’s governor, defined: “We are in a stronger position because we have taken this pause. But we are also very mindful of the fact that this variant is now here in Michigan. It poses a real threat.”

Similarly, Washington, D.C., has just lately reopened indoor eating for the primary time this 12 months. In California, Governor Gavin Newsom has eliminated stay-at-home orders, and eating places and locations of worship can now function outdoor.

In Oregon, officers have introduced that from tomorrow gyms and film theaters can reopen however with restricted capability.

Experts are rightfully cautious about reopening too quickly. Dr. Joshua Sharfstein, vice dean for public health follow and group engagement at Johns Hopkins University in Baltimore, MD, mentioned:

“I do not think it is unreasonable to start to reopen, but if people think that is the green light to pretend the virus does not exist, then we are going to be right back to where we were. If you do restrictions, the virus goes down. You can open up and see how it goes. But if the variants really take hold, that may not be so easy.”

Read extra here.

01/27/2020 09:21 GMT — Problems with EU vaccine rollout

The European Union has been criticized for the gradual tempo of vaccine distribution throughout its member states. In December, the E.U. permitted the acquisition of 300 million doses of the Pfizer-BioNTech vaccine. However, resulting from miscommunication and provide chain issues, Pfizer haven’t been capable of meet expectations.

Read extra concerning the E.U.’s difficulties here.

01/27/2021 09:18 GMT — Eli Lilly’s monoclonal antibody combo therapy reduces COVID-19 severity

A press launch from Eli Lilly outlines encouraging findings from current Phase 3 trials. They discovered {that a} mixture of monoclonal antibodies bamlanivimab (LY-CoV555) and etesevimab (LY-CoV016) reduces the chance of COVID-19 hospitalization and loss of life by 70%.

According to the press launch, the examine included information from 1,035 “high risk patients recently diagnosed with COVID-19.” Of those that obtained the monoclonal antibodies, 2.1% had been hospitalized or died, in contrast with 7% of those that took the placebo.

In whole, there have been 10 deaths, all of which occurred within the placebo group. According to the press launch, “These exciting results, which replicate positive Phase 2 data in a much larger set of patients, add valuable clinical evidence about the role neutralizing antibodies can play in fighting this pandemic.”

Prof. Stephen Evans, a professor of pharmacoepidemiology at London School of Hygiene & Tropical Medicine within the United Kingdom, who was not concerned within the examine, says:

“These results are very encouraging. They are the first antiviral drugs that demonstrably work in the first phase of the disease, just after the virus has infected someone but before it has had time to cause a lot of damage.”

However, Prof. Evans additionally outlines some limitations. For occasion, he’s involved that the fee of the therapy could also be fairly excessive and that the medicine have to be given by infusion.

He additionally questions how a lot of an affect this kind of remedy might have: “Identifying patients who test positive and are at high risk of hospitalization and death prior to their admission to hospital is not simple. It is not clear whether this could be many tens of thousands of patients or relatively few.”

Read the press launch here.

01/26/2021 14:43 GMT — COVID-19 and the mind

Read the complete function here.

01/26/2021 09:35 GMT — Is the AstraZeneca vaccine solely 8% efficient in over 65s?

According to some media outlets, German officers had been involved that the AstraZeneca vaccine won’t be permitted by the European Union as a result of it’s only 8% efficient in adults over 65. However, this seems to be an error.

Read how consultants have reacted to this story here.

01/26/2021 09:26 GMT — COVID-19 and the mind: What do we all know up to now?

How does SARS-CoV-2 have an effect on the mind? A current Medical News Today Special Feature examines the newest proof. The article explores the loss of odor related to COVID-19, its hyperlinks with neurological problems, the function of sedation, how the virus can infect neurons, and extra.

Read the complete function here.

01/25/2021 15:58 GMT — Moderna vaccine efficient in opposition to rising variants

According to a Moderna press release, their COVID-19 vaccine continues to be efficient in opposition to the SARS-CoV-2 variants, B.1.1.7 and B.1.351, which scientists first recognized within the United Kingdom and South Africa, respectively. However, the vaccine had a considerably decreased antibody response to the latter.

Read extra on this story here.

01/25/2021 13:53 GMT — Merck scraps SARS-CoV-2 vaccine

In a press release right now, Merck & Co. introduced that they’re “discontinuing development” of their SARS-CoV-2 vaccines. They clarify that, though the vaccines had been effectively tolerated, “The immune responses were inferior to those seen following natural infection and those reported for other” COVID-19 vaccines.

Find extra on this story in our stay vaccine updates article.

01/25/2021 08:46 GMT — Diabetes therapy might defend in opposition to COVID-19 mortality

In a current examine, scientists discovered that individuals with diabetes present process therapy with the remedy metformin have a considerably decrease danger of loss of life resulting from COVID-19 than these not taking the remedy. The findings seem within the journal Frontiers in Endocrinology.

According to review lead Prof. Anath Shalev: 

“Since similar results have now been obtained in different populations from around the world — including China, France, and a [UnitedHealth] analysis — this suggests that the observed reduction in mortality risk associated with metformin use in [people] with type 2 diabetes and COVID-19 might be generalizable.”

Read MNT’s full write-up of the examine here.

01/25/2021 08:38 GMT — COVID-19 vaccine rollout in Israel: Successes, classes, and caveats

Many think about Israel a world chief within the race to roll out the COVID-19 vaccine. In a current Special Feature, Medical News Today have a look at why the vaccine rollout has been so profitable in Israel and talk about the controversies and fairness points associated to the marketing campaign.

Read the complete function here.

01/22/2021 16:06 GMT — COVID-19: How do inactivated vaccines work?

Read the complete article here.

01/22/2021 09:02 GMT — Antibody drug might defend nursing house residents

According to a current examine, bamlanivimab, a monoclonal antibody drug manufactured by Eli Lilly and Co., helps stop COVID-19 in nursing properties. The examine concerned 299 residents and 666 members of employees. For the residents, bamlanivimab decreased the chance of COVID-19 by 80% throughout a SARS-CoV-2 outbreak.

However, when the researchers analyzed information from the residents and employees collectively, they discovered that the drug decreased the chance of creating COVID-19 signs by 57%. Compared with a placebo, bamlanivimab was additionally related to a decrease danger of COVID-19 mortality and decrease viral hundreds.

The outcomes are encouraging, however as vaccine rollouts deal with older adults, the necessity for medicine of this kind can be decreased. By the time the FDA present a brand new emergency use authorization, comparatively few nursing house residents and employees needs to be left unvaccinated.

Read extra here.

01/22/2021 08:53 GMT — How some individuals in US are receiving shock doses of COVID-19 vaccine

If COVID-19 vaccines thaw or the seal has been punctured, they are going to perish with out use. If photographs stay on the finish of the shift, healthcare staff will typically supply them to individuals who occur to be close to the clinic at closing time. 

However, officers imagine that because the rollout continues to ramp up and extra individuals change into eligible for the shot, fewer and fewer of these leftover doses can be obtainable.

Find extra on this story in our live vaccines update article.

01/21/2021 09:49 GMT — New SARS-CoV-2 variants might affect vaccine effectiveness

A examine, which seems on the preprint server bioRxiv, concludes that the Moderna and Pfizer-BioNtech vaccines could also be much less efficient in opposition to some of the brand new SARS-CoV-2 variants. However, the examine has not but gone by way of the peer-review course of.

Read extra concerning the new variants here.

01/21/2021 09:11 GMT — Some states report working out of vaccine

As the United States ramps up its COVID-19 vaccine rollout, sure areas are reporting difficulties assembly demand. Some states are working out of vaccines and tens of 1000’s of appointments to obtain the primary dose have been cancelled.

Read extra on this story in our live vaccines updates article.

01/20/2021 10:09 GMT — SARS-CoV-2 variant B.1.1.7 detected in 60 nations

According to new information from the World Health Organisation (WHO), the B.1.1.7 variant that scientists within the United Kingdom first reported on the finish of 2020 is now present in 60 nations throughout the globe. Last week, this number stood at 50 nations.

Data from the U.Ok. recommend that B.1.1.7 is ready to unfold extra simply from person to person. 

The WHO additionally state that 23 nations have reported cases of an infection with a variant that they check with as 501Y.V2, which was first recognized in South Africa. An additional set of variants have emerged in Brazil. At the second, it’s not clear whether or not these variants can unfold extra simply between individuals, and the WHO name for extra analysis. 

Read extra about B.1.1.7 here.

01/20/2021 09:00 GMT — First wave of COVID-19 linked to spike in cardiovascular deaths

According to a brand new examine, within the United States, cardiovascular deaths that weren’t straight resulting from COVID-19 surged early within the pandemic. The postponement of procedures, the additional pressure on providers, and sufferers’ avoidance of hospitals might partly clarify the rise.

Find extra particulars on the examine here.

01/20/2021 08:58 GMT — Has the pandemic shifted conventional gender roles in youngster care?

A current examine investigated how the pandemic has influenced conventional gender roles in youngster care. The researchers discovered that youngster care tasks tended to fall to women in the course of the preliminary wave of the COVID-19 pandemic within the United States. The findings seem within theJournal of Applied Psychology.

Overall, the researchers discovered that {couples} working alternating days usually had one of the best outcomes, with each husbands and wives on this class experiencing essentially the most sleep and the bottom psychological misery. The scientists in contrast this with {couples} making an attempt to work in ‘mini-shifts’ or having one father or mother making an attempt to do all of the youngster care.

Read MNT’s protection of the analysis here.

01/19/2021 10:37 GMT — WHO chief warns of ‘catastrophic moral failure’

Speaking on Monday, World Health Organization (WHO) Director-General Tedros Adhanom Ghebreyesus decried the inequity in international vaccine distribution. He mentioned that it is “not right” that younger and healthy individuals in rich nations ought to obtain vaccinations earlier than older individuals and healthcare staff in poorer nations.

Read extra in our live vaccine updates blog.

01/19/2021 09:16 GMT — Vaccines and COVID-19: The newest hopeful analysis

In a current Special Feature, Medical News Today examine the newest COVID-19 vaccine analysis. The writer additionally asks whether or not at present obtainable vaccines can be efficient in opposition to the SARS-CoV-2 variants that scientists have recognized within the United Kingdom, South Africa, and Brazil.

Read the function in full here.

01/19/2021 09:13 GMT — Almost 1 in 3 individuals handled for COVID-19 in hospitals readmitted after discharge

A current examine tracked 47,780 COVID-19 sufferers for nearly 5 months following hospital discharge. They in contrast the outcomes of this group with these of matched people who had been admitted for causes unrelated to COVID-19. The individuals who had obtained hospital therapy for COVID-19 had been 3.5 instances extra prone to be readmitted.

The group handled for COVID-19 had been additionally 7.7 instances extra prone to die than these handled for different causes. The outcomes of the examine seem on the preprint server MedRxiv. Older adults and individuals who weren’t white had the best danger of readmission and loss of life.

The authors conclude: “Individuals discharged from hospital following COVID-19 face elevated rates of multiorgan dysfunction, compared with background levels, and the increase in risk is neither confined to the elderly nor uniform across ethnicities.”

Read extra here.

01/18/2021 09:04 GMT — UK sets lofty vaccination targets

According to officers within the United Kingdom, they goal to provide each grownup within the nation, which is greater than 51 million individuals, at the very least one vaccine dose by September. According to Foreign Secretary Dominic Raab, “If we can do it faster than that, great, but that’s the road map.”Find extra stay vaccine updates here.

Find extra stay vaccine updates here.

01/18/2021 09:00 GMT — SARS-CoV-2 in neurons might harm mind tissue

According to a current examine that concerned mind organoids, genetically engineered mice, and human autopsies, SARS-CoV-2 might infect nerve cells and impede blood stream within the central nervous system. The outcomes seem within the Journal of Experimental Medicine.

Co-senior writer Dr. Kaya Bilguvar explains, “Altogether, our study provides [a] clear demonstration that neurons can become a target of SARS-CoV-2 infection, with devastating consequences of localized ischemia in the brain and cell death.”

Read MNT’s protection of the analysis here.

01/18/2021 08:58 GMT — Most hospitalized COVID-19 sufferers nonetheless have signs after 6 months

A current examine confirmed that greater than three-quarters of a cohort of COVID-19 sufferers nonetheless had at the very least one symptom 6 months after being discharged from the hospital. Dubbed “long COVID,” widespread signs embody fatigue, coughing, muscle aches, chest ache, coronary heart palpitations, and rashes.

The outcomes seem within the journal The Lancet. Corresponding writer Prof. Bin Cao explains that “because COVID-19 is such a new disease, we are only beginning to understand some of its long-term effects on patients’ health.” He continues:

“Our analysis indicates that most patients continue to live with at least some of the effects of the virus after leaving hospital and highlights a need for postdischarge care, particularly for those who experience severe infections.”

Read MNT’s full protection of the analysis here.

01/15/2021 14:39 GMT — How do viral vector vaccines work?

Read the complete article on viral vector vaccines here.

01/15/2021 12:02 GMT — Brazilian variant detected in UK

According to scientists, a brand new variant they imagine to have first appeared in Brazil is already within the United Kingdom. Although the variant is distinct from these first noticed within the U.Ok. and South Africa, it shares sure mutations.

“The Brazilian variant has three key mutations in the spike receptor binding domain (RBD) that largely mirror some of the mutations we are worried about it in the South African variant, hence the concern,” explains Prof. Ravi Gupta, a professor of microbiology on the University of Cambridge within the U.Ok.

“The SARS-CoV-2 RBD is one of the main targets for our immune defences and also the region targeted by vaccines and changes within this region are therefore worrisome. Vaccines are still likely to be effective as a control measure if coverage rates are high and transmission is limited as far as possible.”

Read extra here.

01/15/2021 09:04 GMT — Acute mind dysfunction in ICU sufferers

A current examine finds that in COVID-19 sufferers admitted to the intensive care unit (ICU), episodes of mind dysfunction are extra widespread and extended than these usually related to extreme respiratory failure. The examine seems in The Lancet Respiratory Medicine.

Read extra concerning the examine here.

01/15/2021 09:00 GMT — COVID-19: Gut micro organism might affect severity

The authors of a current examine conclude that a person’s intestine microbiome may have an effect on how their body responds to a SARS-CoV-2 an infection. More particularly, intestine micro organism may affect each the short- and long-term results of the an infection. The outcomes seem within the journal Gut.

Overall, the authors conclude: “Associations between gut microbiota composition, levels of cytokines, and inflammatory markers in patients with COVID-19 suggest that the gut microbiome is involved in the magnitude of COVID-19 severity, possibly via modulating host immune responses.”

The scientists additionally imagine that intestine micro organism might play a job within the improvement of lengthy COVID.

Read MNT’s full protection of the examine here.

01/13/2021 09:02 GMT — Large-scale examine to check interferon beta

Researchers are nonetheless working laborious to determine and trial medicine that may scale back the severity of COVID-19. One such drug is interferon beta. Scientists within the United Kingdom are embarking on a large-scale examine to discover out if it could possibly stop extreme COVID-19 signs from rising.

The experimental therapy is an inhaled model of interferon beta, which biotech firm Synairgen developed at Southampton University Hospital within the U.Ok.

Interferon beta is one of the primary cytokines to be launched throughout an an infection. The protein is the first driver of the immune response within the lung. SARS-CoV-2 suppresses the discharge of interferon beta, and the researchers imagine that by inhaling the cytokine into the lungs, it’ll produce a stronger immune response in opposition to the virus. 

Last 12 months, a smaller study involving 101 individuals produced encouraging outcomes.

As the authors concluded, “Patients who received [interferon beta] had greater odds of improvement and recovered more rapidly from SARS-CoV-2 infection than patients who received placebo, providing a strong rationale for further trials.”

The scientists say that they need to have the ability to full the examine by the summer time.

Read extra here.

01/13/2021 07:56 GMT — What do we all know concerning the new coronavirus variant?

Read the complete function here.

01/12/2021 12:35 GMT — Russia to conduct scientific trial for “Sputnik-Light” vaccine

On Monday, Russian authorities declared that, as a way to guarantee COVID-19 vaccine doses attain sufficient individuals, they are going to check out a one-dose routine of Sputnik V.

Sputnik V is a COVID-19 vaccine developed by the Gamaleya Research Institute of Epidemiology and Microbiology in Moscow, which was first approved for provisional use in Russia final fall.

The experimental one-dose routine is dubbed “Sputnik-Light,” and researchers are set to check it in 150 volunteers.

In the meantime, Russia will proceed to roll out the two-dose Sputnik V vaccination routine.

Russian officers have hinted that if the trial of Sputnik-Light is profitable, they might make the modified vaccine obtainable for export.

According to Kirill Dmitriev, head of the Russian Direct Investment Fund, which funds the brand new trial, “‘Sputnik-Light’ can serve as an effective temporary solution for many countries, which are experiencing a peak of coronavirus infection.”

Read extra here

01/12/2021 10:45 GMT — Immunity in opposition to SARS-CoV-2 might final at the very least 8 months

In a brand new examine revealed in Science, researchers discovered that immune responses that may battle off SARS-CoV-2 have endured for greater than 8 months after individuals recovered from COVID-19.

The staff from La Jolla Institute in California, led by Prof. Alessandro Sette and Prof. Shane Crotty, analyzed 254 blood samples from 188 people who recovered from COVID-19. Of these, 43 samples had been taken at the very least 6 months after the an infection with the virus.

The researchers discovered antibodies, T cells, and reminiscence B cells particular to SARS-CoV-2 to various levels, suggesting immunity to extreme COVID-19 in most examine individuals. However, there was variation, and a few of the volunteers didn’t have important ranges of immunity. 

This could also be why some individuals can develop COVID-19 greater than as soon as.

Read our full evaluation of the analysis here.

01/12/2021 10:11 GMT — Gorillas in San Diego Zoo have COVID-19

After tigers, lions, cats, canines, and mink, gorillas are the newest animals to contract SARS-CoV-2 outdoors of lab research. A press release from the San Diego Zoo, in California, means that the virus possible handed to the gorillas from a employees member with an asymptomatic SARS-CoV-2 an infection.

After two members of the gorilla troop on the zoo started coughing final week, testing of fecal samples confirmed the presence of SARS-CoV-2. 

“Aside from some congestion and coughing, the gorillas are doing well,” Lisa Peterson, the manager director of the San Diego Zoo Safari Park, mentioned. “The troop remains quarantined together and are eating and drinking. We are hopeful for a full recovery.”

Read more about which animals may be susceptible to SARS-CoV-2 infection.

01/11/2021 17:52 GMT — Is there a link between COVID-19 and long-term neurological issues?

Researchers finding out the consequences of previous viral sicknesses, together with the 1918 flu, on cognitive operate recommend that COVID-19 might have long-lasting results on the mind. However, extra analysis is needed to attract any conclusions.

Writing within the journal Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, Dr. Gabriel A. de Erausquin from the University of Texas Health Science Center at San Antonio and collaborators share their perspective on what information from previous viral infections might imply for individuals who get well from COVID-19.

The scientists recommend a link between a person’s danger for neurological problems, resembling Alzheimer’s illness, Parkinson’s illness, and psychological health issues, and an infection with respiratory viruses. Among the viruses, they cite H1N1, which prompted the 1918 flu pandemic, and the SARS-CoV virus, which prompted the 2003 SARS epidemic.

Like the brand new coronavirus, these respiratory viruses are capable of infect cells within the mind. The scientists recommend that even individuals who have had an asymptomatic SARS-CoV-2 an infection could also be at elevated danger of lasting results on the mind.

Scientists might want to run longer-term research to see whether or not they’ll verify this principle.

Read our full evaluation of the work here.

01/08/2021 09:12 GMT — Pfizer examine reveals vaccine efficient in opposition to new variant

Scientists just lately recognized two new strains of SARS-CoV-2 — one of which had been found within the United Kingdom and the opposite in South Africa. A brand new examine concludes that the Pfizer–BioNTech vaccine needs to be efficient in opposition to the U.Ok. variant.

Find extra on this story in our live vaccines update article.

01/08/2021 08:54 GMT — Travelers to England might want to present detrimental COVID-19 check

From subsequent week, people touring to England by boat, aircraft, or train might want to present a detrimental COVID-19 check on arrival. This change brings England in keeping with a number of different nations. Some individuals can be exempt, together with haulers and youngsters beneath 11.

According to Transport Secretary Grant Shapps, “We already have significant measures in place to prevent imported cases of COVID-19, but with new strains of the virus developing internationally, we must take further precautions.”

Britain can be extending the prevailing ban on guests from South Africa. The restrictions now embody all South African nations.

Read extra here.

01/07/2021 08:54 GMT — EU approve Moderna vaccine

On Wednesday, the European Union permitted the Moderna vaccine. The rollout is prone to start subsequent week. According to European Commission President Ursula von der Leyen, “With the Moderna vaccine, the second one now authorized in the European Union, we will have a further 160 million doses. And more vaccines will come.”

Find extra on this story in our live vaccine updates article.

01/07/2021 08:33 GMT — Study finds new proof of SARS-CoV-2 damaging mind blood vessels

In a current examine, scientists didn’t discover SARS-CoV-2 within the brains of individuals with the an infection. However, within the autopsy brains of sufferers who examined constructive for COVID-19, they discovered blood vessel harm brought on by irritation. The outcomes seem within the New England Journal of Medicine.

“We were completely surprised. Originally, we expected to see damage that is caused by a lack of oxygen,” says senior writer Dr. Avindra Nath. “Instead, we saw multifocal areas of damage that is usually associated with strokes and neuroinflammatory diseases.”

Dr. Nath plans to proceed investigating: “In the future, we plan to study how COVID-19 harms the brain’s blood vessels and whether that produces some of the short- and long-term symptoms we see in patients.”

Read MNT’s full protection of the examine here.

01/06/2021 08:50 GMT — Los Angeles hospitals beneath strain

On Monday, health officers in Los Angeles, CA, asked first responders to not carry sufferers who can’t be resuscitated into hospitals. The services are brief on each beds and employees as a result of excessive quantity of COVID-19 sufferers. At some hospitals, ambulances are ready hours to unload sufferers.

On Monday, the state of California reported 72,911 COVID-19 cases, which is the best number because the starting of the pandemic.

Read extra here.

01/05/2021 14:31 GMT — What is vaccine efficacy?

Read the complete function here.

01/05/2021 10:10 GMT — UK begins third lockdown

Yesterday night, the United Kingdom’s prime minister, Boris Johnson, introduced the U.Ok.’s third lockdown. Although the U.Ok. authorities determined to let pupils return to highschool on Monday, they reversed the choice that night. Learning will transfer on-line, whereas individuals ought to do business from home the place doable.

Johnson mentioned the choice is as a result of rise of a brand new variant of SARS-CoV-2, first recognized within the U.Ok. This variant could also be extra transmissible, though it doesn’t seem to extend the chance of worse illness.

For many consultants, this transfer is unsurprising and arrived too late. Dr. Julian W Tang, honorary affiliate professor and scientific virologist on the University of Leicester, says:

“We sort of predicted the likely need for this post-Xmas and New Year lockdown because we knew that many people would still try to meet up over the festive season — and we cannot really blame the new variant virus for all of this.”

He continues, “Yet this brief freedom will have long-term costs for business and education — and people’s health, both COVID-19 and non-COVID-19-related.”

In his televised assertion, Johnson mentioned, “The weeks ahead will be the hardest yet, but I really do believe that we are entering the last phase of the struggle, because with every jab that goes into our arms, we are tilting the odds against [COVID-19] and in favor of the British people.”

Talking concerning the newest U-turn, Dr. Catherine Carroll-Meehan, Head of School of Education and Sociology, University of Portsmouth, says, “Closing schools is the right decision. What families, children, and schools need is some certainty. It is a shame that the government do not take decisions in a more certain and timely manner.”

The new lockdown will proceed till mid-February.

Read extra here.

01/05/2021 09:00 GMT — Is it moral to proceed COVID-19 vaccine trials?

The current authorization of two COVID-19 vaccines for emergency use within the United States poses an moral dilemma for researchers conducting ongoing scientific trials. In explicit, what’s their duty towards individuals who obtained placebo injections? The authors of a current opinion piece deal with this tough query.

Read MNT’s full protection of the paper here.

04/01/2021 09:04 GMT — COVID-19 pandemic 2020: The seek for a vaccine

Since the World Health Organization (WHO) declared the COVID-19 pandemic in March 2020, scientists everywhere in the world have joined the race to develop a secure, efficient vaccine. In a brand new function, Medical News Today define how the seek for a vaccine progressed all through 2020.

Read the complete function here.

04/01/2021 09:01 GMT— US may cut up Moderna vaccine doses in half to hurry up rollout

United States officers have introduced that the federal government is contemplating giving some individuals half doses of the Moderna vaccine to assist pace up the vaccination rollout.

Read extra in our live vaccine update article.

04/01/2021 08:55 GMT — UK start rolling out AstraZeneca vaccine

This morning, officers within the United Kingdom started rolling out the COVID-19 vaccine designed by Oxford University and AstraZeneca. Brian Pinker, 82, was the primary person to obtain the shot. This is the second vaccine at present being rolled out within the U.Ok., following the Pfizer-BioNTech vaccine.

Read extra in our live vaccines update article.

12/23/2020 12:46 GMT — AstraZeneca and Sputnik V builders to check a mixed experimental vaccine

The builders of the Russian Sputnik V vaccine have signed an settlement with AstraZeneca to check a mixture of each vaccines, in line with the Associated Press.  

Read extra in our live vaccine updates article.

12/23/2020 11:26 GMT — Taiwan responds to first case of group transmission since April

On Tuesday, Taiwan noticed its first home case of COVID-19. President Tsai Ing-wen known as for calm, asking individuals to comply with the health authorities’ elevated bodily distancing measures. 

Taiwanese authorities have been fast to hint how the SARS-CoV-2 virus reemerged within the nation. An airline pilot who had flown between the United States and Taiwan has drawn criticism for not disclosing his signs or actions to Taiwanese authorities. He subsequently obtained a constructive check consequence for COVID-19.

An in depth contact of his then obtained a COVID-19 prognosis, making this the primary case of home group transmission since April 12

So far, 170 individuals recognized by way of contact tracing have had a detrimental COVID-19 check consequence, with three individuals nonetheless awaiting their outcomes. 

Taiwan’s authorities launched strict containment measures in response to the emergence of SARS-CoV-2 earlier this 12 months. So far, the nation has seen seven deaths and fewer than 800 cases of COVID-19. 

Read extra here.

12/22/2020 14:20 GMT — MNT Video: How to rejoice winter holidays safely

12/22/2020 12:05 GMT — European Commission grant authorization for BioNTech/Pfizer vaccine

The European Medicines Agency have just lately really useful a conditional advertising and marketing authorization for Cominarty, the BioNTech/Pfizer vaccine, for use in individuals aged 16 years and above.

The European Commission (EC) have granted this authorization, making the BioNTech/Pfizer vaccine the primary one to be administered throughout your complete European Union.

President of the EC Ursula von der Leyen mentioned: “Today, we add an important chapter to a European success story. We approved the first safe and effective vaccine against COVID-19. More vaccines will come soon.”

Read the complete story here and extra about vaccine updates here.

12/22/2020 11:10 GMT — First COVID-19 cases detected in Antarctica 

Antarctica is now not the one continent free of COVID-19. At the General Bernardo O’Higgins Riquelme analysis base, operated by the Chilean Army, 36 Chilean adults examined constructive for the brand new coronavirus.

Of them, 26 are members of the Chilean Army, and 10 are upkeep staff. The military relieved them of their duties after they examined constructive, and evacuated them to the town of Punta Arenas in Chile. They are reportedly self-isolating and in good situation.

Read the complete story here.

12/21/2020 09:31 GMT — Transport ties to UK severed

Scientists within the United Kingdom have recognized a brand new, extra infectious variant of SARS-CoV-2. In response, the U.Ok.’s Prime Minister Boris Johnson outlined new restrictions on Saturday. Consequently, a number of nations have restricted journey to and from the U.Ok.

So far, France, Germany, Italy, the Netherlands, Austria, Switzerland, Ireland, Belgium, Israel, and Canada have shut down journey ties. 

According to consultants, the SARS-CoV-2 variant doesn’t trigger extra extreme illness and shouldn’t intrude with vaccines. However, it seems to unfold extra simply. 

As the U.Ok. prepares to depart the European Union within the subsequent few days, the brand new journey restrictions will add to the already rising chaos.

Read extra here.

12/21/2020 09:05 GMT — US authorizes Moderna vaccine

The FDA have given the Moderna vaccine emergency use authorization (EUA), making it the second vaccine with EUA within the U.S. Already, the U.S. has agreed to buy 200 million doses. Officials expect that healthcare professionals will give the primary photographs this morning.

Find extra element in our vaccine updates article.

12/18/2020 10:20 GMT — Johnson & Johnson announce part 3 scientific trial

Johnson & Johnson just lately introduced a multicountry part 3 scientific trial of their COVID-19 vaccine candidate. The firm have already enrolled round 45,00Zero individuals and, if the vaccine proves secure and efficient, they are going to search for emergency use authorization from the Food and Drug Administration (FDA) in February 2021.

Find extra element in our live vaccine updates article.

12/18/2020 09:14 GMT — Moderna vaccine nears approval

In a gathering yesterday, Food and Drink Administration (FDA) advisors endorsed the emergency use of Moderna’s vaccine. One knowledgeable abstained, however the remaining 20 consultants voted that the advantages of the COVID-19 vaccine outweighed the dangers in individuals aged over 18. The FDA are anticipated to grant emergency use authorization by the tip of the week.

Read extra in our live vaccine updates article.

12/18/2020 09:09 GMT — NICE publish tips on vitamin D and COVID-19

Yesterday, the National Institute for Health and Care Excellence (NICE) launched a assessment of current research on vitamin D and COVID-19. Overall, they conclude that there’s “not enough evidence to support taking vitamin D solely to prevent or treat COVID-19.”

The assessment was performed in collaboration with Public Health England and the Scientific Advisory Committee on Nutrition.

The consultants reviewed information from each observational research and randomized managed trials. They conclude that “It was not possible to determine a direct relationship between vitamin D and COVID-19 based on the available evidence.”

However, as a result of the first supply of vitamin D is daylight, they advise taking the vitamin in the course of the autumn and winter.

The report additionally recommends that researchers proceed investigating the connection between COVID-19 and vitamin D in high-quality randomized managed trials. NICE will proceed to assessment analysis as it’s performed.

Dr. Alison Tedstone, the chief nutritionist at Public Health England, advises that “everyone, particularly the elderly, those who don’t get outside, and those with dark skin, takes a vitamin D supplement containing 10 micrograms [400 international units] every day.”

Read the complete report here.

12/17/2020 09:33 GMT — Guidance on necessary vaccines for workers within the US

The Equal Employment Opportunity Commission (EEOC) have issued steerage for firms which are contemplating making the COVID-19 vaccine necessary. They clarify that employers should be ready to exempt workers with disabilities and spiritual objections.

Read extra in our vaccine updates article here.

12/17/2020 09:14 GMT — What is the protecting worth of totally different face masks?

A current examine assessed how efficient numerous medical and consumer-grade masks are at defending the wearer from publicity to particles comparable in dimension to SARS-CoV-2. The outcomes of the examine seem within the journalJAMA Internal Medicine.

The scientists discovered that essentially the most efficient consumer-grade masks was a washed two-layer woven nylon masks, whereas the least efficient was a three-layer woven cotton masks.

Overall, co-first writer Dr. Phillip Clapp explains that “the fitted filtration efficiencies of many consumer-grade masks were nearly equivalent to or better than surgical masks.”

Read extra concerning the findings here.

12/16/2020 09:17 GMT — Vaccine developed by British American Tobacco permitted for human trials in US

This week, the U.S. health regulator permitted a vaccine developed by British American Tobacco (BAT) for human trials. The vaccine, developed by BAT’s biotech subsidiary, Kentucky BioProcessing, derives from tobacco leaves. Enrollment for the examine is prone to start shortly. BAT expect scientific trials to start in late June 2021. 

Find extra on this story in our vaccine updates article.

12/16/2020 09:09 GMT — BMJ editors query UK lockdown easing for Christmas

In a uncommon transfer, the editors of BMJ have penned a joint article. They criticize the federal government of the United Kingdom’s choice to ease COVID-19 measures across the Christmas interval. The authors are involved that the transfer will overwhelm the National Health Service (NHS).

In the article, which is simply the second joint editorial in 100 years of the journal’s existence, the authors clarify that “The planned relaxation of restrictions over Christmas will boost [case] numbers further as the NHS also struggles with the additional demands of winter.”

They fear that the U.Ok. public “will see the lifting of restrictions over Christmas as permission to drop their guard.” Beyond the affect on the general public, the editors are involved about NHS employees; they write:

“Of particular concern is the effect on staff, many of whom have already worked through the hardest 9 months of their professional lives. Levels of burnout and sickness absence are likely to exceed those already experienced.”

Read the editorial here.

12/16/2020 09:01 GMT — How have we developed vaccines so shortly?

As nations start rolling out vaccines, Medical News Today spoke with a number of medical consultants to find out how scientists have created COVID-19 vaccines so swiftly with out compromising security.

Read the function here.

12/15/2020 14:49 GMT — Moderna vaccine attracts nearer to emergency use authorization

According to Food and Drug Administration’s reviewers, the Moderna vaccine is 95% efficient. Importantly, the group didn’t increase any security considerations. The FDA launched the information in a 54-page document earlier right now. The group will talk about the findings in a vaccine panel assembly on Thursday. 

Read extra in our stay vaccines article here.

12/15/2020 10:18 GMT — New SARS-CoV-2 variant recognized in England

Yesterday, the United Kingdom’s health secretary, Matt Hancock, introduced that scientists had recognized a brand new variant of SARS-CoV-2 in England. He defined that it was significantly prevalent within the South, which had just lately skilled a pointy rise in cases.

Local authorities have recorded at the very least 60 COVID-19 cases that contain the brand new variant, Hancock reported, including that there was “nothing to suggest” that the variant prompted extra extreme illness or might restrict the consequences of vaccines.

During a press convention, Chief Medical Officer for England Chris Whitty defined: “There are many variants. It just happens that this one has quite a few more mutations than some of the other variants, so that’s the reason why we’ve taken it particularly seriously.”

He continued, “But there’s nothing to suggest that the symptoms are different, that the testing is different, or that the clinical outcome is different for this variant.”

In an interview with the BBC, Prof. Alan McNally, an knowledgeable in microbial genomics on the University of Birmingham, mentioned:

“Let’s not be hysterical. It doesn’t mean it’s more transmissible or more infectious or dangerous. It is something to keep an eye on. Huge efforts are ongoing at characterizing the variant and understanding its emergence. It is important to keep a calm and rational perspective on the strain, as this is normal virus evolution and we expect new variants to come and go and emerge over time.”

Dr. Zania Stamataki, a viral immunologist on the identical establishment, offered added insight: “The emergence of different coronavirus strains a year after SARS-CoV-2 first jumped to humans is neither cause for panic nor unexpected. […] This virus doesn’t mutate as fast as influenza and, although we need to keep it under surveillance, it will not be a major undertaking to update the new vaccines when necessary in the future.”

Read extra here.

12/15/2020 08:57 GMT — Long COVID and durations: The affect on feminine well-being

A number of individuals with long COVID have reported an affect on their menstrual cycles. In a brand new function, Medical News Today spoke with two medical consultants and six people who’ve been experiencing these disruptive modifications to their menstrual cycles.

Read the complete function here.

12/14/2020 15:24 GMT — First New York healthcare employee receives vaccine

Today, Sandra Lindsay turned the primary healthcare employee to obtain the Pfizer–BioNTech COVID-19 vaccine in New York. The intensive care unit nurse obtained the vaccine at Long Island Jewish Medical Center in Queens, one of the epicenters of COVID-19 earlier this 12 months.

Find extra vaccine updates here.

12/14/2020 09:27 GMT — FDA concern emergency use authorization for COVID-19 vaccine

On Friday, the Food and Drug Administration (FDA) issued emergency use authorization for the Pfizer-BioNTech vaccine. The FDA concluded that the “potential benefits [of the vaccine] outweigh the known and potential risks […].” The first shipments of the vaccine left FedEx and UPS services in Tennessee and Kentucky yesterday.

Read extra on this story here.

12/14/2020 09:05 GMT — One-third of sufferers might expertise ‘long COVID’

A brand new examine finds that 32% of individuals who examined constructive for SARS-CoV-2 had been nonetheless experiencing at the very least one symptom 6 weeks after their exams. The most typical of these signs had been fatigue, shortness of breath, and a loss of style or odor.

Read MNT’s full protection of the examine here.

12/11/2020 14:51 GMT — Video: Spotlight on 3 vaccine frontrunners

Read the complete article here.

12/11/2020 09:31 GMT — Study hints that dietary supplements might scale back COVID-19 danger in females

A current examine discovered small however important decreases within the danger of SARS-CoV-2 an infection amongst females who took multivitamins, vitamin D, omega-3 fatty acids, or probiotics. The examine has not but been by way of the peer assessment course of and seems on the preprint server MedRxiv.

Although the outcomes appear hopeful, Naveed Sattar, a professor of metabolic medication on the University of Glasgow, within the United Kingdom, who was not concerned within the analysis, provides some perspective:

“These are interesting results, but due to the way the study has been conducted, these data absolutely cannot tell us that taking such supplements ‘protects’ against infection [resulting in] COVID-19.”

The scientists had been stunned that the impact was solely important in females. They theorize that this is perhaps as a result of females have extra sturdy immune techniques. Alternately, they is perhaps extra prone to put on masks or wash their palms than males.

Prof. Seif Shaheen, from Queen Mary University of London, provides additional context: “A major concern is that these findings may be confounded by socioeconomic status, given that individuals of higher status are more likely to take supplements and are also less likely to become infected with SARS-CoV-2.”

Read MNT’s full protection of the analysis here.

12/11/2020 08:59 GMT — FDA consultants advocate Pfizer-BioNtech vaccine

Yesterday, a panel of consultants who advise the Food and Drug Administration (FDA) really useful that the group ought to give the Pfizer-BioNTech COVID-19 vaccine emergency approval. The committee voted 17–4 that the advantages of the vaccine outweigh the dangers for individuals aged 16 years and older. 

Read extra about this story here.

12/10/2020 09:18 GMT — Two allergic reactions to COVID-19 vaccine reported in UK on first day of roll-out

Yesterday, the United Kingdom started rolling out the Pfizer BioNTech COVID-19 vaccine. According to the pinnacle of Britain’s medication regulator, two individuals had allergic reactions shortly after receiving it. Both have since recovered.

Find extra info here.

12/10/2020 09:07 GMT — COVID-19: Once hospitalized, Black sufferers are much less prone to die

Research reveals that within the United States, some populations, together with people who find themselves Black, usually tend to develop COVID-19. After controlling for underlying situations and common neighborhood revenue, a brand new examine reveals that after Black sufferers are hospitalized, they’re much less prone to die of the illness than white sufferers.

If confirmed, these findings assist the concept that structural determinants of health account for a disproportionately increased price of out-of-hospital COVID-19 deaths in in Black and Hispanic communities.

Read MNT’s full protection of the examine here.

12/10/2020 09:03 GMT — Smartphone-based system might detect SARS-CoV-2

Scientists are developing a conveyable system that provides fast, correct check outcomes with the assistance of an everyday smartphone digicam. By estimating the number of virus particles in samples, the system might additionally decide an an infection’s progress.

Find extra details about this expertise here.

12/09/2020 09:21 GMT — ‘Oxford’ vaccine: Results from part 3 trial

Yesterday, The Lancet revealed the outcomes of part 3 scientific trials investigating AstraZeneca’s so-called Oxford vaccine. The examine concerned individuals within the United Kingdom, Brazil, and South Africa. Overall, the outcomes present that the vaccine candidate protects in opposition to the symptomatic illness in 70% of cases.

Read extra in our live vaccines update article.

12/09/2020 09:15 GMT — COVID-19 case on cruise ship

After an 83-year-old passenger examined constructive for SARS-CoV-2, a Royal Caribbean cruise ship departing from Singapore needed to return to dock. The crew needed to confine all passengers to their cabins.

Each passenger required polymerase chain response testing for SARS-CoV-2 earlier than becoming a member of the “cruise-to-nowhere.” Despite this security measure, one passenger reported to the onboard medical heart with diarrhea and examined constructive for the virus.

People in shut contact with the person had additionally needed to bear testing, however nobody else acquired the an infection. All passengers can even bear additional testing earlier than they’re allowed to depart the terminal.

Read extra here.

12/09/2020 09:07 GMT — Pfizer vaccine nearer to authorization in US

Recently, Pfizer and BioNTech introduced that their vaccine candidate was 95% efficient in opposition to COVID-19. They are at present working with the Food and Drug Administration (FDA) to safe approval for emergency use. This week, the FDA launched paperwork declaring no points with security or efficacy.

Read extra in our live vaccines update article.

12/08/2020 09:46 GMT — UK begins mass vaccinations

Today, the United Kingdom turned the primary Western nation to start mass vaccinations. Health Secretary Matt Hancock known as the day “V-day.” In Coventry, 90-year-old Margaret Keenan turned the primary person to obtain the vaccine outdoors of scientific trials.

Find extra info in our live vaccine update article.

12/08/2020 09:30 GMT — Fauci voices considerations about Christmas interval

Yesterday, in an interview with CNN, Dr. Anthony Fauci warned of one other surge in cases after the Christmas and New Year holidays. He had voiced considerations earlier than Thanksgiving and explains that over the upcoming holidays, the issue can be “compounded because it’s a longer holiday.”

He additionally suggested that “We’re at a very critical time. […] We’ve got to not walk away from the facts and the data. This is tough going for all of us.” President-elect Joe Biden has asked Dr. Fauci to be his COVID chief medical advisor.

Read extra here.

12/07/2020 09:54 GMT — South Korea experiences new wave of COVID-19 cases

Despite their preliminary success at controlling the pandemic, South Korea is experiencing growing numbers of cases. As of Sunday, the Korea Disease Control and Prevention Agency report that there are 8,311 individuals in quarantine, which is the best number to this point.

Read extra here.

12/07/2020 09:51 GMT — ‘Clear, balanced information’ necessary for vaccine uptake

In a current editorial, David Phizackerley, the deputy editor of the journal Drug and Therapeutics Bulletin, argues that clear and balanced info on the efficacy and security of the COVID-19 vaccines is necessary for making certain their broad uptake.

Find extra element in our stay vaccine updates article.

12/07/2020 09:46 GMT — Adapted yellow fever vaccine might defend in opposition to COVID-19

A current examine concludes {that a} genetically altered yellow fever vaccine is very efficient in stopping SARS-CoV-2 an infection in animals. If it passes scientific trials, the brand new vaccine would have some benefits over different SARS-CoV-2 vaccines. For occasion, it offered safety after only one shot.

Find extra element in our stay vaccine updates article.

12/04/2020 10:15 GMT — Three former presidents keen to take the vaccine publicly

In an effort to spice up public confidence, three former presidents — George W. Bush, Bill Clinton, and Barack Obama — have all publicly acknowledged that they might be ready to take the COVID-19 vaccine as soon as it receives approval.

Find extra on this story in our live vaccine update article.

12/04/2020 09:40 GMT — Dr. Fauci apologizes for claiming UK rushed choice

Earlier this week, Dr. Anthony S. Fauci, sparked controversy when he claimed that the United Kingdom had not acted as rigorously as the Food and Drug Administration (FDA) when it licensed its first COVID-19 vaccine. Yesterday, he apologized and mentioned he has “great faith” within the U.Ok. regulators.

Find extra about this story here.

12/04/2020 09:28 GMT — Link between air air pollution and COVID-19 spikes recognized

The authors of a current examine conclude that temperature inversions and Saharan mud storms could also be contributing to localized peaks of COVID-19. The analysis seems within the journal Earth Systems and Environment.

Find MNT’s protection of the analysis here.

12/03/2020 09:31 GMT — Russia plans large-scale COVID-19 vaccination plan

On Wednesday, Russian President Vladimir Putin introduced a large-scale vaccination program that can start subsequent week. Doctors and academics can be first in line for the vaccine. Some consultants are involved because the Sputnik V vaccine is but to finish superior scientific trials for security.

Read extra concerning the Russian vaccine here.

12/03/2020 09:16 GMT — AstraZeneca’s US vaccine trial outcomes due early 2021

Yesterday, the chief adviser for the United States authorities’s Operation Warp Speed program introduced that outcomes from AstraZeneca’s U.S. vaccine trials might be obtainable early subsequent 12 months. If the outcomes are encouraging, they are going to possible file for an emergency authorization from the Food and Drug Administration (FDA).

Visit our vaccine live updates article for extra info.

12/03/2020 08:53 GMT — Do SARS-CoV-2 mutations have an effect on its transmissibility?

A current examine analyzed samples of the SARS-CoV-2 genome from 46,723 individuals in 99 nations. The authors conclude that no at present recognized mutation of SARS-CoV-2 seems to make the virus higher at transmitting. The outcomes seem within the journalNature Communications.

Read MNT’s full protection of the analysis here.

12/02/2020 08:57 GMT — UK licenses vaccine in opposition to COVID-19 

The Medicines and Healthcare merchandise Regulatory Authority (MHRA) within the United Kingdom have authorized the Pfizer/BioNTech vaccine for emergency use. The U.Ok. has already bought 40 million doses of the vaccine, and the primary 10 million doses ought to arrive this month.

Find extra particulars in our stay vaccine updates article.

12/02/2020 08:52 GMT — Developing an equation to foretell transmission charges

In a current study, scientists developed an equation that may assist decide the possible number of individuals who would possible contract SARS-CoV-2 from a single person with the virus at differing types of occasions. They additionally investigated which interventions can be handiest within the totally different eventualities.

Read extra concerning the examine here.

12/02/2020 08:49 GMT — The FDA transfer towards vaccine approval

On Tuesday, Food and Drug Administration (FDA) Commissioner Stephen Hahn mentioned it was doable that the FDA would approve Pfizer’s experimental vaccine earlier than the tip of the 12 months. However, within the ABC News interview, he explained that “it’s hard to predict. […] We need everything to fall into place.”

Read extra concerning the vaccine push within the United States here.

12/01/2020 11:49 GMT — Recommendations for vaccine allocation due

Today, the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices will meet to make their suggestions on who will obtain the primary COVID-19 vaccines. The panel consists of impartial consultants and one client consultant. 

According to the New York Times, the members will possible advocate that healthcare employees and residents of nursing properties and different long-term care services will obtain the primary batches of vaccines, as soon as the Food and Drug Administration (FDA) grant emergency use approval. 

Watch the stay assembly here at 19:00 GMT

12/01/2020 11:49 GMT — A photograph captures the pressure on ICU sufferers and health staff

A photograph taken on Thanksgiving inside a COVID-19 intensive care unit (ICU) at United Memorial Medical Center in Houston, TX, reveals Chief of Staff Dr. Joseph Varon in full private protecting tools hugging a affected person. 

Photographer Go Nakamura took the photograph for Getty Images whereas documenting the work of healthcare professionals and the fact of being in an ICU with COVID-19.

Dr. Varon has been working for greater than 250 consecutive days. He discovered the COVID-19 affected person out of his hospital mattress, in tears, searching for assist. He was asking for his spouse. 

“I was feeling sad, just like him, and I was just recollecting all the patients that I have had to do similar things with,” Dr. Varon explains. “I would go into their rooms, sit on their beds, and chat with them because they truly need somebody.”

Read extra here.

11/30/2020 14:57 GMT — Moderna apply for approval for mRNA vaccine candidate within the US and Europe

Today, Moderna introduced the completion of their part 3 scientific trial main efficacy evaluation. The vaccine candidate is 94.1% efficient in opposition to COVID-19 and 100% efficient in opposition to extreme COVID-19. The firm will apply right now for emergency use approval within the United States. 

In addition, it will additionally apply to the European Medicines Agency for conditional advertising and marketing authorization.

In a press release, Moderna highlighted that 196 individuals enrolled of their 30,000-participant trial have now had COVID-19. Of them, 11 had been within the group that had obtained the vaccine. 

There had been 30 cases of extreme COVID-19, all within the placebo group. One person on this group died. 

The 196 cases of COVID-19 within the examine occurred amongst numerous individuals, together with older adults and people from minority ethnic teams.

The firm pressured that they will submit the outcomes of the examine to a peer reviewed journal. 

Read extra vaccine updates here.

11/30/2020 12:55 GMT — Tuberculosis vaccine might assist defend in opposition to COVID-19

A retrospective, observational examine has discovered that the BCG vaccination — which goals to stop tuberculosis — might defend in opposition to an infection with the novel coronavirus.

The examine discovered that amongst 6,201 healthcare staff, those that had had the BCG vaccination had been much less prone to have antibodies to the SARS-CoV-2 virus of their blood and fewer prone to report having skilled COVID-19 signs in contrast with those that had not had the vaccine. 

Read our full protection of the examine here.

11/27/2020 17:30 GMT — High blood sugar ranges might predict COVID-19 loss of life danger

New analysis finds that top blood sugar ranges correlate with a better danger of COVID-19 mortality, even in individuals who shouldn’t have a historical past of diabetes. 

The new examine — which seems within the journal Annals of Medicine — discovered that 41.1% of those that died from COVID-19 had very excessive blood sugar ranges. 

The danger of dying from COVID-19 rose proportionately with blood sugar ranges, and the affiliation was impartial of diabetes standing.

“Early glycemic control may be a suitable therapeutic option to reduce the poor outcomes in hospitalized, hyperglycemic COVID-19 patients with or without a previous diabetes diagnosis,” write the examine authors.

Read the complete story here

11/27/2020 11:20 GMT — Antibleeding drug might successfully deal with COVID-19

Researchers at Goethe University in Frankfurt, Germany, led a brand new examine exhibiting that the antibleeding drug aprotinin (Trasylol) can cease the brand new coronavirus from coming into healthy host cells. 

The scientists performed experiments in numerous sorts of human cell, utilizing totally different concentrations of the drug, and in three totally different strains of the virus. 

As the researchers level out, what is critical is that the drug was efficient at a dose that individuals can realistically take — i.e., a therapeutic dose.

Senior examine writer Prof. Jindrich Cinatl, from the Institute for Medical Virology at University Hospital Frankfurt, says, “Our findings show that aprotinin is effective against SARS-CoV-2 in concentrations that can be achieved in patients.”

“In aprotinin, we have a drug candidate for the treatment of COVID-19 that is already approved for other indications and could readily be tested in patients.”

Read our full protection of the examine here.

11/26/2020 10:26 GMT — Scientists within the Netherlands plan ‘human challenge’ vaccine examine

Scientists from Leiden University Medical Center (LUMC) within the Netherlands are hoping to intentionally transmit SARS-CoV-2 to individuals to check vaccine efficacy. Already, 240 individuals have stepped ahead to take part within the “human challenge” trial.

Read extra about this story in our live vaccine updates article.

11/26/2020 09:03 GMT — Many mother and father need to rejoice Thanksgiving with others regardless of danger

A brand new ballot reveals that, regardless of the risks, 61% of mother and father who often meet with prolonged household at Thanksgiving intend to fulfill them in person this 12 months. The report was revealed by the C.S. Mott Children’s Hospital, on the University of Michigan.

Read extra concerning the outcomes here.

11/26/2020 08:50 GMT — COVID-19 has produced ‘alarming’ improve in loneliness

A current survey reveals that the COVID-19 pandemic is having a troubling impact on the psychological health of younger adults within the United States. In the survey of 1,008 individuals aged 18–35, 80% of individuals reported “significant depressive symptoms” in the course of the pandemic.

The outcomes of the examine seem within the Journal of Psychoactive Drugs. “These young adults are the future of our nation’s social fabric,” says Dr. Viviana Horigian, the lead writer of the examine. “They need to be given access to psychological help, coupled with the development and dissemination of brief online contact-based interventions that encourage healthy lifestyles.”

Read MNT’s full protection of the examine here.

11/25/2020 15:15 GMT — MNT Video replace: Thanksgiving and psychological health

11/25/2020 08:56 GMT — NIH promise to spice up COVID-19 testing in ‘underserved and vulnerable populations’

According to a news release from the National Institutes of Health (NIH), they’re offering further funding to “enable and enhance COVID-19 testing of populations disproportionately affected by the disease.” This consists of individuals from marginalized ethnic backgrounds, older adults, people who find themselves incarcerated, and people who find themselves homeless.  

The NIH clarify that they’ve “awarded practically $45 million to broaden the analysis community of the Rapid Acceleration of Diagnostics Underserved Populations (RADx-UP) program.” 

The RADx-UP program focuses on, amongst different issues, creating and validating point-of-care and home-based exams.

Find extra element here.

11/25/2020 08:51 GMT — Officials urge individuals to remain house at Thanksgiving

As COVID-19 case numbers attain report highs within the United States, health consultants and politicians throughout the nation are urging individuals to remain house this Thanksgiving. In the final month, greater than half of U.S. governors have imposed or introduced again statewide measures.

On Tuesday, greater than 87,00Zero individuals had been being handled in hospitalsfor COVID-19, which is an all-time report. U.S. Surgeon General Jerome Adams asked individuals to grasp “the severity of the moment. […] We just need you, the American people, to hold on a little bit longer.”

In his weekly COVID briefing, California’s prime health official, Dr. Mark Ghaly, urged individuals to say “no” to household gatherings. He wrote, “Saying ‘no’ to people you love is never easy, […] but knowing how and when to say ‘no’ is the first step to protecting your health and the health of the people you care about.”

Read extra here.

11/24/2020 09:35 GMT — US authorities plans to start distributing Regeneron’s antibody mixture

According to U.S. officers, the authorities will quickly start distributing Regeneron’s antibody remedy for COVID-19. The transfer comes following emergency use authorization from the Food and Drug Administration (FDA). The mixture of two monoclonal antibodies, known as REGN-COV2, helps deal with mild-to-moderate COVID-19 in adults and youngsters.

Read extra here.

11/24/2020 09:23 GMT — Despite warnings, many individuals within the US plan to journey for Thanksgiving

On Sunday, regardless of growing numbers of COVID-19 cases, greater than 1 million passengers handed by way of airport safety within the United States. The American Automobile Association predict that 45–50 million individuals will use the highways throughout Thanksgiving 2020, down from 55 million in 2019.

Read extra here.

11/23/2020 11:44 GMT — What explains Africa’s profitable response to the COVID-19 pandemic?

In an opinion piece, written for MNT, Prof. Agnes Binagwaho, M.D., MPEd, Ph.D. — vice-chancellor of the University of Global Health Equity in Kigali, Rwanda — and her analysis affiliate Kedest Mathewos clarify why African nations fared a lot better than their Western counterparts within the battle in opposition to COVID-19.

Read the article here.

11/23/2020 09:52 GMT — AstraZeneca’s ‘Oxford’ vaccine 70% efficient

According to a press release, the experimental COVID-19 vaccine developed by Oxford University and AstraZeneca prevents 70.4% of individuals from creating COVID-19. Although that is decrease than the Moderna and Pfizer vaccines, utilizing a distinct dosing routine may improve the determine to 90%.

The current announcement is predicated on information from 24,00Zero individuals within the United Kingdom, Brazil, and South Africa. Importantly, the Oxford vaccine is cheaper to provide and simpler to retailer and transport than the Moderna and Pfizer choices.

The trial concerned two dosing regimens. One consisted of two full doses, which offered 62% safety. The different concerned one half dose adopted by one full dose, which offered 90% safety. Prof. Andrew Pollard, the director of the Oxford Vaccine Group and the chief investigator of the Oxford Vaccine Trial, explains:

“These findings show that we have an effective vaccine that will save many lives. Excitingly, we’ve found that one of our dosing regimens may be around 90% effective, and if this dosing [regimen] is used, more people could be vaccinated with planned vaccine supply.”

Dr. Stephen Griffin, an affiliate professor within the School of Medicine at the University of Leeds, U.Ok., says:

“This is yet more excellent news and should be considered tremendously exciting. The Oxford vaccine, as for the others we’ve heard about recently, is capable of generating 90% protection against COVID-19. Given the favorable stability seen for this vaccine, it has great potential to be delivered across the globe, achieving huge public health benefits.”

Dr. Griffin was not concerned with the examine.

Read extra here.

11/23/2020 09:49 GMT — Black, Hispanic individuals account for half of hospital deaths

According to a current evaluation, within the first 6 months of 2020, 53% of deaths from COVID-19 in 88 hospitals throughout the United States had been Black or Hispanic sufferers. The evaluation outcomes seem within the journal Circulation.

Read extra concerning the examine here.

11/20/2020 09:19 GMT — UK might ease guidelines for Christmas

Currently, the United Kingdom is within the midst of a 4-week lockdown. According to U.Ok. health minister Matt Hancock, the lockdown is having the specified impact and case numbers are plateauing. He hopes that restrictions is perhaps partially eased in time for Christmas.

Hancock defined that “There are encouraging signs that the number of cases is starting to flatten. […] It, of course, won’t be like a normal Christmas, there will have to be rules in place, but we hope that they’ll allow for a bit more of that normal Christmas.”

Read extra here.

11/20/2020 09:16 GMT — WHO launch assertion relating to remdesivir

In an article, which seems in BMJ, the World Health Organization (WHO) advocate “against the use of remdesivir in hospitalized patients with COVID-19.” This change in stance is a response to outcomes from the WHO SOLIDARITY trial. The outcomes first appeared on the preprint server medRxiv on October 15. 

The authors of the examine, which investigated a number of COVID-19 interventions, conclude that “[r]emdesivir, [h]ydroxychloroquine, [l]opinavir, and [I]nterferon regimens appeared to have little or no effect on hospitalized COVID-19, as indicated by overall mortality, initiation of ventilation, and duration of hospital stay.”

The authors of the current BMJ replace clarify that, though they might not categorically state that remdesivir affords no profit, “there is no evidence based on currently available data that it does improve patient-important outcomes.”

Read extra here.

11/19/2020 10:31 GMT — Pfizer and BioNTech COVID-19 candidate vaccine 95% efficient

In a press release, Pfizer and BioNTech have introduced the outcomes from their part 3 scientific trial: their vaccine is 95% efficient. These outcomes construct on preliminary outcomes announced final week. According to the press launch, “[e]fficacy was consistent across age, gender, race, and ethnicity demographics” and in individuals over 65. 

The researchers enrolled 43,00Zero individuals within the examine and recognized no important security considerations. The mRNA vaccine candidate is known as BNT162.

According to the press launch, “[t]he companies expect to produce, globally, up to 50 million vaccine doses in 2020 and up to 1.3 billion doses by the end of 2021.”

Read extra here

11/19/2020 09:11 GMT — In-person instructing ceases in New York City

Due to a surge in case numbers in New York City, the town’s public college system has halted in-classroom instructing. Mayor Bill de Blasio introduced the modifications yesterday on Twitter, explaining that “[w]e must fight back the second wave of COVID-19.”

Read extra here.

11/19/2020 08:55 GMT — Arthritis drug might enhance COVID-19 survival in older adults

A drug used to deal with arthritis reveals promising preliminary outcomes for treating COVID-19 in older adults. A small examine discovered that COVID-19 sufferers taking baricitinib had been much less prone to want mechanical air flow and extra prone to survive than people who weren’t taking the drug.

The examine, which seems within the journal Science Advances, concerned simply 83 sufferers with a mean age of 81. To verify the findings, scientists are already conducting bigger randomized managed trials.

Read extra concerning the ongoing analysis here.

Previous COVID-19 updates obtainable right here:

September 19–December 19

August 18–September 18

June 17–August 17

April 16–June 16

March 24-April 15

March 7–March 23

Feb 22–March 6

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